Oxamides as novel NR2B selective NMDA receptor antagonists

Formalin test in mice, a useful technique for evaluating mild analgesics

Steinar Hunskaar, Ole Bernt Fasmer, Kjell Hole · Journal of Neuroscience Methods · 1985 · 822 citations

Medicine, Pharmacology, Experimental Pharmacology +12

Ro 25–6981, a Highly Potent and Selective Blocker of N-Methyl-d-aspartate Receptors Containing the NR2B Subunit. Characterization in Vitro

G. Fischer, Vincent Mutel, Gerhard Trube et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 484 citations

Life Sciences, Neuroscience, Pharmacology +17

Efficacy of Spinal NMDA Receptor Antagonism in Formalin Hyperalgesia and Nerve Injury Evoked Allodynia in the Rat

Sandra R. Chaplan, Annika B. Malmberg, Tony L. Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1997 · 373 citations

Medicine, Neuroscience, Pharmacology +17

Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn

S. Boyce, A. C. Wyatt, J.K. Webb et al. · Neuropharmacology · 1999 · 338 citations

Life Sciences, Neuroscience, Pharmacology +17

(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D-Aspartate Responses

B. L. CHENARD, J. Bordner, Todd W. Butler et al. · Journal of Medicinal Chemistry · 1995 · 179 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14