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The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor

Aliphatic Isothiocyanates SulforaphaneWeak AgonistsBiochemistryFunctional SelectivityMedicineAryl Hydrocarbon ReceptorMechanism Of ActionReceptor (Biochemistry)Organic ChemistryPharmacotherapyPharmacologyDrug Discovery