Accounts of Chemical Research · 2007 · 176 citations · 35 references
Natural SciencesChemical BiologyChemistryPhysical ChemistryRedox BiochemistryTheoretical ChemistryChemical BondingCluster ChemistryCoordination ChemistryMetal-ligand BondingRedox ChemistryRedox ProcessesCluster ReactivityCopper-binding SitesElectron DelocalizationElectronic CorrelationsMixed-valence Metal ClustersOxygen Activation By Metal CentersRedox Chemistry Of ClustersStructure-reactivity Relationships
Copper-cluster sites in biology exhibit unique spectroscopic features reflecting exchange coupling between oxidized Cu's and e (-) delocalization in mixed valent sites. These novel electronic structures play critical roles in O 2 binding and activation for electrophilic aromatic attack and H-atom abstraction, the 4e (-)/4H (+) reduction of O 2 to H 2O, and in the 2e (-)/2H (+) reduction of N 2O. These electronic structure/reactivity correlations are summarized below.
35
Oxygen Binding, Activation, and Reduction to Water by Copper Proteins
Edward I. Solomon, Peng Chen, Markus Metz et al. · Angewandte Chemie International Edition · 2001 · 831 citations · Full text
Reversible Cleavage and Formation of the Dioxygen O-O Bond Within a Dicopper Complex
J.A. Halfen, Samiran Mahapatra, Elizabeth Wilkinson et al. · Science · 1996 · 545 citations
Dioxygen Binds End-On to Mononuclear Copper in a Precatalytic Enzyme Complex
Sean T. Prigge, Betty Eipper, Richard E. Mains et al. · Science · 2004 · 413 citations