New antibiotics, griseusins A and B isolation and characterization.

Abstract

New antibiotics, griseusins A and B were isolated from a strain of Streptomyces griseus. Both antibiotics have a 5-hydroxy-1, 4-naphthoquinone chromophore and their molecular formulae were determined to be C22H20O10 and C22H22O10, respectively. The griseusins are active against gram-positive bacteria.