Histologic Characteristics and Mucin Immunohistochemistry of Cystic Fibrosis Sinus Mucosa

Abstract

Significant SMG hyperplasia and a trend toward increased glandular MUC5B expression exist in children with CRS/CF. This suggests that SMG hyperplasia and glandular MUC5B mucin contribute to mucus overproduction in the sinus mucosa of this population.