Inhibition of Poly(ADP-Ribose) Polymerase Enhances the Toxicity of<sup>131</sup>I-Metaiodobenzylguanidine/Topotecan Combination Therapy to Cells and Xenografts That Express the Noradrenaline Transporter - Concepedia

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Inhibition of Poly(ADP-Ribose) Polymerase Enhances the Toxicity of<sup>131</sup>I-Metaiodobenzylguanidine/Topotecan Combination Therapy to Cells and Xenografts That Express the Noradrenaline Transporter

DOI Full Paper Access

27

Citations

33

References

2012

Year

A. McCluskey, Robert J. Mairs, Mathias Tesson, Sally L. Pimlott, John W. Babich, Mark N. Gaze, Sue Champion, Marie Boyd

Journal of Nuclear Medicine

Abstract

The antitumor efficacy of topotecan, (131)I-MIBG, and (131)I-MIBG/topotecan combination treatment was increased by PARP-1 inhibition in vitro and in vivo.

References

	Year	Citations

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