Intermolecular Conjugate Addition of Pyrroloindoline and Furoindoline Radicals to α,β‐Unsaturated Enones <i>via</i> Photoredox Catalysis

Abstract

Abstract We have developed an intermolecular conjugate addition of 3a‐pyrroloindoline/furoindoline radicals to α,β‐unsaturated enones, through visible‐light photoredox catalysis. Ir(ppy) 2 (dtbbpy) PF 6 was found to be an effective promoter to initiate this reaction from readily available 3a‐bromopyrroloindolines/furoindolines. This method was exploited to prepare a series of indole terpenoid‐like compounds of potential biological interest. magnified image