Persistence of a Positive (1,3)-β- <scp>d</scp> -Glucan Test after Clearance of Candidemia in Hematopoietic Stem Cell Transplant Recipients

Abstract

In 6 hematopoietic stem cell transplant (HSCT) recipients with candidemia, the (1,3)-β-d-glucan (BG) test was positive a median of 2.5 days after a positive blood culture. Only in 1 patient did BG positivity precede positive blood cultures. BG concentrations decreased in patients with clinical response, but positive BG results persisted long after blood cultures became sterile (median, 48 days).