Thrombotic Microangiopathy and Peritubular Capillary C4d Expression in Renal Allograft Biopsies

Abstract

TMA was infrequent in this series of unselected, consecutive, renal allograft biopsies (3.4%). PTC C4d may be a significant risk factor for early TMA, and TMA is associated with glomerular thrombi and neutrophilic capillaritis. TMA in allografts with suspected AMR may portend a higher risk of graft loss.