Lesional Overexpression of Matrix Metalloproteinase-9 Promotes Intraplaque Hemorrhage in Advanced Lesions But Not at Earlier Stages of Atherogenesis - Concepedia

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Lesional Overexpression of Matrix Metalloproteinase-9 Promotes Intraplaque Hemorrhage in Advanced Lesions But Not at Earlier Stages of Atherogenesis

227

Citations

31

References

2005

Year

Ramon de Nooijer, C.J.N. Verkleij, Jan H. von der Thüsen, J. Wouter Jukema, E. E. van der Wall, Th.J.C. van Berkel, Andrew H. Baker, E.A.L. Biessen

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

These data show a differential effect of MMP-9 at various stages of plaque progression and suggest that lesion-targeted MMP-9 inhibition might be a valuable therapeutic modality in stabilizing advanced plaques, but not at earlier stages of lesion progression.

References

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