Methylation of <i>P16</i>, <i>P21</i>, <i>P27</i>, <i>RB1</i> and <i>P53</i> genes in odontogenic keratocysts

Abstract

Our data show methylation of the promoter of P21 gene in OKCs. In addition, methylation of the P27 and RB1 genes are commonly found in dental follicles. Further studies are necessary to determine the functional relevance of these alterations.