Concepedia

Publication | Closed Access

Effect of Simvastatin on Cetuximab Resistance in Human Colorectal Cancer With KRAS Mutations

DOI

101

Citations

34

References

2011

Year

Jeeyun Lee, In‐Kyoung Lee, Boram Han, Joon Oh Park, Jiryeon Jang, Chaehwa Park, Won Ki Kang
JNCI Journal of the National Cancer Institute

Abstract

Simvastatin may overcome cetuximab resistance in colon cancer cells with KRAS mutations by modulating BRAF activity and inducing apoptosis.

References

YearCitations

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