Transient Neonatal Diabetes, <i>ZFP57</i>, and Hypomethylation of Multiple Imprinted Loci

Abstract

There is yet no clear genotype-epigenotype-phenotype correlation to explain the variable clinical presentation, and this results in difficulties predicting the prognosis of affected individuals. However, many cases have a more severe phenotype than seen in other causes of TNDM1. Further cases and global epigenetic testing are needed to clarify this.