Structural Nucleotide Analogs Are Potent Activators/Inhibitors of Pancreatic β Cell KATP Channels: An Emerging Mechanism Supporting Their Use as Antidiabetic Drugs

Switching from Insulin to Oral Sulfonylureas in Patients with Diabetes Due to Kir6.2 Mutations

Ewan R. Pearson, Isabelle Flechtner, Pål R. Njølstad et al. · New England Journal of Medicine · 2006 · 986 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Mutations in ATP-Sensitive K+ Channel Genes Cause Transient Neonatal Diabetes and Permanent Diabetes in Childhood or Adulthood

Sarah E. Flanagan, Ann‐Marie Patch, Deborah Mackay et al. · Diabetes · 2007 · 358 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Sulfonylurea Induced β-Cell Apoptosis in Cultured Human Islets

Kathrin Maedler, Richard D. Carr, Domenico Bosco et al. · The Journal of Clinical Endocrinology & Metabolism · 2005 · 334 citations · Full text

Medicine, Endocrinology, Pharmacology +15

Pharmaco-topology of Sulfonylurea Receptors

Andrey P. Babenko, Gabriela González, Joseph Bryan · Journal of Biological Chemistry · 2000 · 131 citations · Full text

Natural Sciences, Pharmacology, Physiology +17

Mitochondrial ATP-Sensitive Potassium Channel Activation Protects Cerebellar Granule Neurons From Apoptosis Induced by Oxidative Stress

Yasushi Teshima, Masaharu Akao, Ronald A. Li et al. · Stroke · 2003 · 125 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17