Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer

Rolf Sauer, Heinz Becker, Werner Hohenberger, Claus Rödel, Christian Wittekind, Rainer Fietkau, Peter Martus, Jörg Tschmelitsch, E. Hager, Clemens F. Hess,

New England Journal of Medicine · 2004 · 6K citations · 12 references

Abstract

Preoperative chemoradiotherapy, as compared with postoperative chemoradiotherapy, improved local control and was associated with reduced toxicity but did not improve overall survival.

References

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