New England Journal of Medicine · 2004 · 6K citations · 12 references
Preoperative chemoradiotherapy, as compared with postoperative chemoradiotherapy, improved local control and was associated with reduced toxicity but did not improve overall survival.
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Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma
James E. Krook, C G Moertel, Leonard L. Gunderson et al. · New England Journal of Medicine · 1991 · 1.9K citations