Treatment of Travelers' Diarrhea: Ciprofloxacin plus Loperamide Compared with Ciprofloxacin Alone

Abstract

In a region where enterotoxigenic E. coli was the predominant cause of travelers' diarrhea, loperamide combined with ciprofloxacin was not better than treatment with ciprofloxacin alone. Loperamide appeared to have some benefit in the first 24 hours of treatment in patients infected with enterotoxigenic E. coli. Both regimens were safe.