Stereoselective Multiple Functionalization of Pyrylium Salts by Domino Reactions with 2-Silyloxybuta-1,3-dienes

Kim Goldenstein, Frank Döring, C. Lehmann, Mathias Noltemeyer

Angewandte Chemie International Edition · 2001 · 12 citations · 17 references

DOIFull text

Open access

Concepts

Abstract

Six at a time! Up to six stereogenic centers can be diastereoselectively formed in one step in three-component domino reactions of 4-silyloxypyrylium triflates with 2-silyloxybuta-1,3-dienes. Annulated or bridged ring systems such as 1 and 2, respectively, can be formed with high selectivity. R1=silyl group; R2, R3=organyl group.

References

17