Infection of swine <i>ex vivo</i> tissues with avian viruses including H7N9 and correlation with glycomic analysis

Abstract

In contrast to previous studies we found that there was not as much expression of Siaα2-3 glycans on the surface of the trachea. Infection of Siaα2-3 binding avian viruses was restricted to the lower respiratory tract bronchioles. This finding may diminish the ability of the swine to act as an intermediary in the transmission of avian viruses to humans.