Relationship between ovarian cortisol:cortisone ratios and the clinical outcome of <i>in vitro</i> fertilization and embryo transfer (IVF‐ET)

Abstract

Concentrations of both cortisol and cortisone were significantly lower in FF samples obtained from patients that conceived by IVF-ET than in those obtained from nonconception cycles. Conception by gonadotrophin-stimulated IVF-ET was associated with an elevated intrafollicular ratio of cortisol:cortisone, consistent with a low level of intraovarian cortisol oxidation by 11betaHSD.