Oxidative Palladium(II)‐Catalyzed Dehydrogenative CH/CH Cross‐Coupling of 2,3‐Substituted Indolines with Arenes at the C7 Position

Abstract

Directed directing group: The C7 position of the indoline nucleus is difficult to address in CH activation. An oxidative palladium(II) catalysis that allows for cross-dehydrogenative coupling in that position with activation of the CH bond of the arene component is disclosed here. This CH/CH cross-coupling is applicable to various indolines acetylated at the nitrogen atom. Substitution at C2 is crucial for the CH activation to occur at C7 (see scheme). As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.