Concepedia

Thieno[2,3-c]Isoquinolin-5-one, a Potent Poly(ADP-Ribose) Polymerase Inhibitor, Promotes Atherosclerotic Plaque Regression in High-Fat Diet-Fed Apolipoprotein E-Deficient Mice: Effects on Inflammatory Markers and Lipid Content

Chetan P. Hans, Mourad Zerfaoui, Amarjit S. Naura, Dana Troxclair, Jack P. Strong, Khalid Matrougui, A. Hamid Boulares

Journal of Pharmacology and Experimental Therapeutics · 2009 · 50 citations · 18 references

DOIFull text

Open access

Concepts

References

18

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

Hyo Chol Ha, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1999 · 907 citations · Full text

, , +15

Role of Poly(ADP-ribose) Polymerase (PARP) Cleavage in Apoptosis

A. Hamid Boulares, Alexander G. Yakovlev, Vessela S. Ivanova et al. · Journal of Biological Chemistry · 1999 · 899 citations · Full text

, , +11

Institute of Laboratory Animal Resources.

Thomas L. Wolfle · 1995 · 618 citations

, , +12

Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading

James X. Rong, Mark S. Shapiro, Eugene Trogan et al. · Proceedings of the National Academy of Sciences · 2003 · 552 citations · Full text

, , +11

Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E–Deficient Mice

Anne Braun, Bernardo L. Trigatti, Mark J. Post et al. · Circulation Research · 2002 · 487 citations

, , +15