Concepedia

Impact of Perineural Invasion in the Pathologically N0 Neck in Oral Cavity Squamous Cell Carcinoma

Steven B. Chinn, Matthew E. Spector, Emily L. Bellile, Jonathan B. McHugh, Thomas Gernon, Carol R. Bradford, Gregory T. Wolf, Avraham Eisbruch, Douglas B. Chepeha

Otolaryngology · 2013 · 119 citations · 11 references

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Abstract

PNI is an independent adverse risk factor in the absence of nodal metastasis and extracapsular spread. We observed a statistically significantly longer DFI and LRC when patients were treated with adjuvant radiation.

References

11

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

Jay S. Cooper, Thomas F. Pajak, Arlene A. Forastiere et al. · New England Journal of Medicine · 2004 · 3.2K citations

Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer

Jacques Bernier, C. Domenge, Mahmut Özsahin et al. · New England Journal of Medicine · 2004 · 3.1K citations · Full text

The National Comprehensive Cancer Network (NCCN).

Elizabeth H. Wood · Europe PMC (PubMed Central) · 2004 · 2.9K citations · Full text

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Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

Jacques Bernier, Jay S. Cooper, Thomas F. Pajak et al. · Head & Neck · 2005 · 1.7K citations

, , +18

Oral Squamous Cell Carcinoma

Margaret Brandwein‐Gensler, Miriam S. Teixeira, Carol M. Lewis et al. · The American Journal of Surgical Pathology · 2005 · 804 citations