Molecular mechanisms of ovarian hyperstimulation syndrome: paracrine reduction of endothelial claudin 5 by hCG in vitro is associated with increased endothelial permeability

Miriam Rodewald, Daniel Herr, W. Colin Duncan, Hamish M. Fraser, G Hack, F. Gagsteiger, R. Kreienberg, Christine Wulff

Human Reproduction · 2009 · 41 citations · 36 references

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Abstract

For OHSS, this novel paradigm suggests that hCG can increase endothelial permeability by up-regulating VEGF in LGCs which causes reduction in endothelial claudin 5 expression.

References

36