Concepedia

GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP

Brian D. Green, Katharine Hand, Janette E. Dougan, Bronagh McDonnell, Roslyn Cassidy, David Grieve

Archives of Biochemistry and Biophysics · 2008 · 150 citations · 32 references

Open access

Concepts

Life SciencesPharmacologyPhysiologyCell SignalingMolecular PharmacologySignal TransductionCardiovascular PhysiologyG Protein-coupled Receptor SignalingGlucagon-like Peptide-1 Receptor AgonistsIon Channel PharmacologyIon Channel PhysiologyPancreatic HormonesGlucagon-like Peptide-1 Receptor SignalingGlucagon-like PeptidesProtein Kinase G Signaling

References

32

Diabetes and cardiovascular disease. The Framingham study

William B. Kannel · JAMA · 1979 · 4K citations

Medicine, Cardiology, Endocrinology +17

Diabetes and Cardiovascular Disease

William B. Kannel · JAMA · 1979 · 2.8K citations

Medicine, Endocrinology, Internal Medicine +12

Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum

Rolf Mentlein, Baptist Gallwitz, Wolfgang E. Schmidt · European Journal of Biochemistry · 1993 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.

Carolyn F. Deacon, Anders H. Johnsen, Jens J. Holst · The Journal of Clinical Endocrinology & Metabolism · 1995 · 757 citations

Life Sciences, Biochemistry, Endocrinology +16

Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease

Thomas Nyström, M. Gutniak, Qimin Zhang et al. · American Journal of Physiology-Endocrinology and Metabolism · 2004 · 671 citations

Medicine, Cardiology, Endocrinology +17