A <sub>1</sub> Adenosine Receptor Upregulation Accompanies Decreasing Myocardial Adenosine Levels in Mice With Left Ventricular Dysfunction - Concepedia

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A <sub>1</sub> Adenosine Receptor Upregulation Accompanies Decreasing Myocardial Adenosine Levels in Mice With Left Ventricular Dysfunction

DOI Full Paper Access

36

Citations

46

References

2007

Year

Hajime Funakoshi, Lefteris C. Zacharia, Zhonghua Tang, Jin Zhang, Ling L. Lee, Julie C. Good, David E. Herrmann, Yoshihiro Higuchi, Walter J. Koch, Edwin K. Jackson,

Abstract

Cardiac dysfunction secondary to the overexpression of TNF is associated with marked alterations in myocardial levels of adenosine and ARs. Modulation of the myocardial adenosine system and its signaling pathways may be a novel therapeutic target in patients with heart failure.

References

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