Concepedia

Comparative Effectiveness of Beta-Lactams Versus Vancomycin for Treatment of Methicillin-Susceptible<i>Staphylococcus aureus</i>Bloodstream Infections Among 122 Hospitals

Jennifer S. McDanel, Eli N. Perencevich, Daniel J. Diekema, Loreen A. Herwaldt, Tara C. Smith, Elizabeth A. Chrischilles, Jeffrey D. Dawson, Lan Jiang, Michihiko Goto, Marin L. Schweizer

Clinical Infectious Diseases · 2015 · 218 citations · 17 references

DOIFull text

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Abstract

For patients with MSSA bloodstream infections, beta-lactams are superior to vancomycin for definitive therapy but not for empiric treatment. Patients should receive beta-lactams for definitive therapy, specifically antistaphylococcal penicillins or cefazolin.

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