The effect of duration of dose delivery with patient‐controlled analgesia on the incidence of nausea and vomiting after hysterectomy

Abstract

Reasons for these unexpected findings remain speculative. The high incidence of PONV appears to be inherently high in gynaecological surgery patients and standard antiemetic medication regimens appear to be poorly efficacious. Reasons for the differences in the time-course of emetic episodes between the two groups may be related to differences in the time-course of central opioid receptor occupancy.