Absent correlation between vaginal bleeding and oestradiol levels or endometrial morphology during tibolone use in early postmenopausal women

Prospective double-blind trial of synthetic steroid (Org OD 14) for preventing postmenopausal osteoporosis.

Robert Lindsay, D.M. Hart, A. Kraszewski · BMJ · 1980 · 152 citations · Full text

Pharmacy, Gynecology, Pharmacotherapy +17

Tibolone: prevention of bone loss in late postmenopausal women.

N. H. Bjarnason, Ketil Bjarnason, Jens Haarbo et al. · The Journal of Clinical Endocrinology & Metabolism · 1996 · 143 citations · Full text

Medicine, Biochemistry, Endocrinology +17

In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD-14) and its metabolites on human endometrium

Leszek Markiewicz, Erlio Gurpide · Journal of Steroid Biochemistry · 1990 · 113 citations

Medicine, Endocrinology, Pharmacology +12

Human endometrial 3β-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/progestagenic activity ratios of a steroidal drug (Org OD 14)

Baiging Tang, Leszek Markiewicz, Helenius J. Kloosterboer et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1993 · 106 citations

Life Sciences, Biochemistry, Pharmacology +15

Effects of two doses of tibolone on trabecular and cortical bone loss in early postmenopausal women: A two-year randomized, placebo-controlled study

Bernd Berning, Cornelis van Kuijk, J. W. Kuiper et al. · Bone · 1996 · 86 citations

Medicine, Endocrinology, Pharmacotherapy +15