Human Molecular Genetics · 1995 · 93 citations · 0 references
Life SciencesGeneticsMolecular GeneticsCytogeneticsHuman GeneticsMedical GeneticsGene MappingGenetic DisordersGenetic SyndromesHearing ImpairmentHearing LossRare Disease GeneticsGenetic Inner Ear DisordersHearing Loss EtiologyNon-syndromic Hearing LossSyndromic Hearing Loss
Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL). The latter is more common and is highly heterogeneous. To date, six NSHL loci have been mapped. We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.