Hepatocyte Nuclear Factors 4α and 1α Regulate Kidney Developmental Expression of Drug-Metabolizing Enzymes and Drug Transporters

An integrated encyclopedia of DNA elements in the human genome

Nature · 2012 · 18.9K citations · Full text

Chromatin, Dna Sequencing, Dna +12

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14K citations · Full text

Transcriptional Regulation, B Cell Identities, Cell Lineage +9

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Nathaniel D. Heintzman, Rhona Stuart, Gary C. Hon et al. · Nature Genetics · 2007 · 3.4K citations

Histone Modifications, Chromatin, Transcriptional Regulation +14

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham, Anshul Kundaje, Shelley Force Aldred et al. · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · 2012 · 2.8K citations · Full text

Histone modifications at human enhancers reflect global cell-type-specific gene expression

Nathaniel D. Heintzman, Gary C. Hon, R. David Hawkins et al. · Nature · 2009 · 2.5K citations · Full text

Histone Modifications, Chromatin, Chromatin Structure +11