2004 · 30 citations · 18 references
EngineeringBig Data IndexingPattern DiscoveryPattern MiningBioinformatics DatabaseText MiningQuery SequenceInformation RetrievalData ScienceData MiningData IntegrationBiostatisticsLarge DatabasesData ManagementBiological DatabaseKnowledge DiscoveryComputer ScienceBioinformaticsData IndexingFrequent Pattern MiningDna MicroarrayComputational BiologyIndexing Technique
We present an index structure for managing weighted-sequences in large databases. A weighted-sequence is defined as a two-dimensional structure where each element in the sequence is associated with a weight. A series of network events, for instance, is a weighted-sequence in that each event has a timestamp. Querying a large sequence database by events' occurrence patterns is a first step towards understanding the temporal causal relationships among the events. The index structure proposed enables us to efficiently retrieve from the database all subsequences, possibly noncontiguous, that match a given query sequence both by events and by weights. The index method also takes into consideration the nonuniformfrequency distribution of events in the sequence data. In addition, our method finds a broad range of applications in indexing scientific data consisting of multiple numerical columns for discovery of correlations among these columns. For instance, indexing a DNA microarray that records expression levels of genes under different conditions enables us to search for genes whose responses to various experimental perturbations follow a given pattern. We demonstrate, using real-world data sets, that our method is effective and efficient.
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R. K. Agrawal, Ramakrishnan Srikant · 2002 · 5.1K citations
Relational Queries, Knowledge Discovery In Databases, Engineering +15
Biclustering of expression data.
Yao Cheng, George M. Church · PubMed · 2000 · 2.1K citations