Circulation · 2013 · 296 citations · 76 references
MedicineCardiologyPreventive MedicineClinical CardiologyPreventive CardiologyRisk Factor AnalysisBlood Pressure ManagementCardiometabolic Risk ReductionCardiovascular DiseaseCardiovascular Disease PreventionCardiovascular MedicineLipid-lowering TherapyAutonomic ToneCardiovascular Disease ManagementCardiovascular Risk Factor ModificationSympathetic Nervous System ResponsesSympathetic Responding
C ardiovascular disease (CVD) is the leading cause of death in the United States. 1 Despite efforts promoting primary and secondary CVD prevention, 2-8 obesity and physical inactivity remain at epidemic proportions, with >60% of Americans adults overweight or obese and >50% not performing recommended levels of physical activity. 9 Similarly, hypertension, hypercholesterolemia, and other CVD risk factors remain poorly controlled in many Americans. Despite numerous pharmacological and device-based advances in the management of patients with established CVD, morbidity and mortality associated with this condition remain substantial. Hence, a critical need exists for novel strategies and interventions that can potentially reduce the risk of CVD and its attendant morbidity and mortality.
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Task Force of the European Society of Cardiology the North A Electrophysiology · Circulation · 1996 · 16.9K citations
Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
Marek Malik, J. Thomas Bigger, A. John Camm et al. · European Heart Journal · 1996 · 15.3K citations · Full text
Nursing, Cardiology, Physiology +15