Concepedia

On the reductive amination of aldehydes and ketones catalyzed by homogeneous Rh(i) complexes

Vitali I. Tararov, Renat Kadyrov, Armin Börner, Thomas H. Riermeier

Chemical Communications · 2000 · 102 citations · 7 references

DOI

Concepts

Abstract

The homogeneously catalyzed reductive amination of aldehydes and ketones under smooth conditions is reported, showing for the first time, that Rh(I) catalysts based on chelating diphosphines and diphosphinites can be advantageously employed for this reaction, even for the production of chiral amino acid derivatives.

References

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Reductive N-alkylation of amides, carbamates and ureas

Daniel Dubé, Andrew A. Scholte · Tetrahedron Letters · 1999 · 114 citations

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Rhodium(I) catalyzed asymmetric hydrogenation of enamines

Vitali I. Tararov, Renat Kadyrov, Thomas H. Riermeier et al. · Tetrahedron Letters · 2000 · 67 citations

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Involvement of Free Nitrenium Ions, Ion Pairs, and Preassociation Trapping in the Reactions of Ester Derivatives of N-Arylhydroxylamines and N-Arylhydroxamic Acids in Aqueous Solution

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Phosphines versus phosphinites as ligands in the rhodium catalyzed asymmetric hydrogenation of imines: a systematic study

Vitali I. Tararov, Renat Kadyrov, Thomas H. Riermeier et al. · Tetrahedron Asymmetry · 1999 · 43 citations

, , +8