Diagnostic and Prognostic Value of <i>BCL2</i> Rearrangement in 53 Patients With Follicular Lymphoma Presenting as Primary Skin Lesions

Abstract

We observed that BCL2 rearrangement in PCFCL is rare, associated with initial positivity of staging (diagnostic value) or with secondary extracutaneous spreading (prognostic value). In selected cases with BCL2-CD10 coexpression, FISH testing could detect patients with poor outcome and require closer monitoring.