Patterning Mammalian Cells for Modeling Three Types of Naturally Occurring Cell–Cell Interactions

Abstract

Types of stripes: Microfluidic techniques are combined with surface chemistry to pattern multiple types of cells on the same substrate to simulate three types of naturally occurring cell–cell interactions. PDMS=poly(dimethylsiloxane) stamp, FN=fibronectin to promote cell adhesion, SAM=self-assembled monolayer of an applied alkanethiol that resists cell adhesion. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.