Tissue Doppler echocardiography reliably reflects severity of iron overload in pediatric patients with β thalassemia

Abstract

Decreased DT, increased PVAR-MVA duration, and increased E/Em ratio reliably reflected severe iron overload in pediatric patients with beta thalassemia. Systolic and diastolic LV function is preserved in patients who have serum ferritin <2500 ng/mL.