Atropisomerism of α,β‐Unsaturated Amidines: Stereoselective Synthesis by Catalytic Cascade Reaction and Optical Resolution

Abstract

Torquoselective: Enantiomers of axially chiral α,β-unsaturated amidines were prepared by catalytic cascade reactions consisting of [2+2] cycloaddition and thermal cycloreversion. The cascade reaction proceeds in a stereoselective (torquoselective) manner, confirmed by the intermediate depicted. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.