Effects of Selective α ₁ - and α ₂ -Adrenergic Blockade on Coronary Flow Reserve After Coronary Stenting

Abstract

Urapidil and yohimbine attenuated the CFR impairment occurring after revascularization by increasing both the epicardial vasodilator effect of adenosine and the blood flow velocity, thus suggesting that the adrenergic system plays an important role in limiting the capacity of the coronary circulation to dilate.