Concepedia

High Variability between Results of Different In-House Tests for Cytomegalovirus (CMV) Monitoring and a Standardized Quantitative Plasma CMV PCR Assay

Lutz von Müller, W. Hampl, Joachim Hinz, Helga Meisel, Angela Reip, Elisabeth Engelmann, Regine Heilbronn, Barbara C. Gärtner, Oliver H. Krämer, Hermann Einsele,

Journal of Clinical Microbiology · 2002 · 39 citations · 9 references

DOIFull text

Open access

Concepts

Abstract

A total of 2,718 blood samples were analyzed in five virological laboratories for the presence of cytomegalovirus (CMV) by in-house tests and one standardized plasma PCR assay. Results from in-house tests showed remarkable variability. Detection of CMV pp65 antigen or DNA from cells was more sensitive than that by plasma CMV PCR assay.

References

9

Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation

Vincent C. Emery, Caroline Sabin, Alethea Cope et al. · The Lancet · 2000 · 553 citations

, , +14

Polymerase chain reaction monitoring reduces the incidence of cytomegalovirus disease and the duration and side effects of antiviral therapy after bone marrow transplantation

H Einsele, Gerhard Ehninger, Holger Hebart et al. · Blood · 1995 · 454 citations · Full text

, , +16

LEVELS OF VIRUS-SPECIFIC CD4 T CELLS CORRELATE WITH CYTOMEGALOVIRUS CONTROL AND PREDICT VIRUS-INDUCED DISEASE AFTER RENAL TRANSPLANTATION1

Martina Sester, Urban Sester, Barbara C. Gärtner et al. · Transplantation · 2001 · 256 citations

, , +17

The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during an active cytomegalovirus infection

Johanna M. M. Grefte, Bernardina T.F. van der Gun, S. Schmolke et al. · Journal of General Virology · 1992 · 144 citations

, , +14

PLASMA POLYMERASE CHAIN REACTION FOR CYTOMEGALOVIRUS DNA AFTER ALLOGENEIC MARROW TRANSPLANTATION

Michael Boeckh, Ghislaine Gallez‐Hawkins, David Myerson et al. · Transplantation · 1997 · 141 citations

, , +12