Concepedia

Catalyst Free Indirect Friedländer Synthesis of Substituted Quinolines from Alcohols in PEG‐400

Fang‐Wen Wu, Rei‐Sheu Hou, Huey‐Min Wang, Iou‐Jiun Kang, Ling‐Ching Chen

Journal of the Chinese Chemical Society · 2012 · 12 citations · 48 references

DOI

Abstract

Abstract The synthesis of substituted quinolines can be easily and greenly accomplished by the direct reaction between the corresponding aminoalcohol and ketone using PEG‐400 as reaction medium in the presence of a base, without any transition‐metal catalyst.

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