Targeted Deletion of the Extracellular Signal-Regulated Protein Kinase 5 Attenuates Hypertrophic Response and Promotes Pressure Overload–Induced Apoptosis in the Heart - Concepedia

Concepedia

Publication | Open Access

Targeted Deletion of the Extracellular Signal-Regulated Protein Kinase 5 Attenuates Hypertrophic Response and Promotes Pressure Overload–Induced Apoptosis in the Heart

DOI Full Paper Access

81

Citations

38

References

2010

Year

Tomomi Kimura, Jiawei Jin, Min Zi, Sukhpal Prehar, Wei Liu, Delvac Oceandy, Jun‐ichi Abe, Ludwig Neyses, A.H. Weston, Elizabeth J. Cartwright,

Circulation Research

Abstract

These results reveal an important function of ERK5 in cardiac hypertrophic remodeling and cardiomyocyte survival. The role of ERK5 in hypertrophic remodeling is likely to be mediated via the regulation of MEF2 activity.

References

	Year	Citations

Page 1