Shuttle‐Based Fluorogenic Silver‐Cluster Biolabels

Abstract

Clustering together: A shuttle-based fluorogenic cluster transfer, in which silver clusters (SCs) are directly transferred from a low-molecular-weight poly(acrylic acid) (PA) shuttle to a single-stranded DNA (ssDNA) tag on the protein of interest (see picture), proceeds with excellent specificity. Upon transfer, the cluster fluorescence increases more than ten times, which provides bright, photostable labeling. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.