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Procyanidins from Tormentil: Fractionation and Study of the Anti-radical Activity towards Superoxide Anion.
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1994
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Anti-radical ActivitiesOrganic ChemistryChemical BiologyRedox BiologyPolyphenolicsOxidative StressStandardised Water-soluble ExtractPhytopharmacologyAnalytical ChemistryPotentilla TormentillaPhytochemicalChromatographyBiochemistryBioassay-guided IsolationRadical (Chemistry)Reactive Oxygen SpeciePharmacologyNatural SciencesPhytochemistryMedicineDrug Analysis
A standardised water-soluble extract was prepared from rhizomes of Potentilla tormentilla. The procyanidins in the extract were fractionated according to their degree of polymerisation by chromatography on Sephadex LH20. The anti-radical activities of the different fractions towards superoxide anion were compared when pentamers and hexamers were found to be the most active.