MR imaging of bone marrow in children with osteosarcoma: effect of granulocyte colony-stimulating factor.

Abstract

The findings suggest that GCSF causes changes in the MR imaging appearance of marrow. Histologic correlation supports the hypothesis that these changes are attributable to reconversion from fatty to hematopoietic marrow. Awareness of this finding is important to avoid false-positive diagnosis of marrow metastases.