Hydrophilic and Hydrophobic Bile Acids Exhibit Different Cytotoxicities Through Cytolysis, Interleukin-8 Synthesis and Apoptosis in the Intestinal Epithelial Cell Lines. IEC-6 and Caco-2 cells

Abstract

These results strongly suggest that HDCA induces cytotoxicity through its ability to induce apoptosis rather than its detergent effect.