Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography

Kathryn E. deKrafft, Zhigang Xie, Guohua Cao, Sylvie Tran, Liqing Ma, Otto Zhou, Wenbin Lin

Angewandte Chemie International Edition · 2009 · 247 citations · 18 references

Concepts

Abstract

Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse-phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure).

References

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