On the Polymorphism of Aspirin

Abstract

More headaches with aspirin: No new polymorph? Reduction and re-indexing of X-ray data collected on a crystal of the well-known form I of aspirin in a unit cell recently reported for the new form II results in a data set from which this so-called new form can be obtained and even refined isotropically! Form II, if it exists, needs to be identified with more rigorous experimentation and modeling.