Concepedia

Treatment of Former Smokers With 9-cis-Retinoic Acid Reverses Loss of Retinoic Acid Receptor-  Expression in the Bronchial Epithelium: Results From a Randomized Placebo-Controlled Trial

Jonathan M. Kurie, R. Lotan, J. Jack Lee, Jack Lee, Rodolfo C. Morice, D. D. Liu, Xiao Xu, Fadlo R. Khuri, Jae Y. Ro, Walter N. Hittelman,

JNCI Journal of the National Cancer Institute · 2003 · 89 citations · 31 references

DOIFull text

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Abstract

9-cis-RA treatment can restore RAR-beta expression in the bronchial epithelium of former smokers, raising the possibility that this retinoid has potential chemopreventive properties in former smokers.

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