Concepedia

Impacts of Cytosolic Phospholipase A2, 15-Prostaglandin Dehydrogenase, and Cyclooxygenase-2 Expressions on Tumor Progression in Colorectal Cancer

Sung‐Chul Lim, Hoon Cho, Tae Bum Lee, Cheol Hee Choi, Young Don Min, Sung Soo Kim, Kyung Jong Kim

Yonsei Medical Journal · 2010 · 38 citations · 36 references

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Abstract

The present study demonstrates that cPLA2 and mPGES-1, in addition to COX-2, are constitutively overexpressed, and that 15-PGDH might be attenuated in colorectal cancer. Furthermore, cPLA2 and 15-PGDH as well as COX-2 could have an important role in tumor progression.

References

36

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Kotha Subbaramaiah, Nasser K. Altorki, Wen Jing Chung et al. · Journal of Biological Chemistry · 1999 · 350 citations · Full text