A Double-Blind Randomized Controlled Trial of <i>N</i> -Acetylcysteine in Cannabis-Dependent Adolescents

Abstract

This is the first randomized controlled trial of pharmacotherapy for cannabis dependence in any age group to yield a positive primary cessation outcome in an intent-to-treat analysis. Findings support NAC as a pharmacotherapy to complement psychosocial treatment for cannabis dependence in adolescents.